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Ricostruzione ipotetica dell'aspetto di un cacciatore raccoglitore mesolitico europeo: pelle scura, occhi azzurri |
There is nothing like a little ancient DNA weirdness to start off 2014, which promises to be as exciting as 2013 was.
The new study La Brana 1 identifies it as ancestral in the
SLC24A5 locus in which virtually all Europeans are derived. This comes in the heels of the Loschbour
preprint which identified that sample from Luxembourg as also being ancestral. Taken together, it's now clear that
hunter-gatherers from Mesolithic Western Europe were brown.
Curiously, it now seems that both Europe and India were (in part) inhabited by brown people and became lighter by a
process of admixture + selection. The process went "all the way" in Europe, but a cline of pigmentation was sustained in India.
The other finding (not mentioned in the abstract) is that La Brana 1 belonged to
Y-haplogroup C6! This is a low-frequency European clade of haplogroup C. So now, we have evidence that haplogroup C is not eastern Eurasian (as the presence of its subclades in Australia, India, East Asia, and the Americas might suggest), but a pan-Eurasian entity. It remains to be seen whether this C-in-Europe can be pushed further back in time, but finding it in Mesolithic Iberia reduces the chance that it's some random eastern Eurasian who made it to the outskirts of Europe recently.
Finally, La Brana 1 has derived alleles at loci associated with pathogen resistance. This might be important, because a common hypothesis is that Europeans developed this type of resistance during the Neolithic as they started interacting with the pathogens of domesticated species and started living in less-hygienic higher-density settlements.
Nature (2014) doi:10.1038/nature12960
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European
Iñigo Olalde et al.
Ancient genomic sequences have started to reveal the origin and the demographic impact of farmers from the Neolithic period spreading into Europe1, 2, 3. The adoption of farming, stock breeding and sedentary societies during the Neolithic may have resulted in adaptive changes in genes associated with immunity and diet. However, the limited data available from earlier hunter-gatherers preclude an understanding of the selective processes associated with this crucial transition to agriculture in recent human evolution. Here we sequence an approximately 7,000-year-old Mesolithic skeleton discovered at the La Braña-Arintero site in León, Spain, to retrieve a complete pre-agricultural European human genome. Analysis of this genome in the context of other ancient samples suggests the existence of a
common ancient genomic signature across western and central Eurasia from the Upper Paleolithic to the Mesolithic. The La Braña individual carries ancestral alleles in several skin pigmentation genes, suggesting that the light skin of modern Europeans was not yet ubiquitous in Mesolithic times. Moreover, we provide evidence that a significant number of derived, putatively adaptive variants associated with pathogen resistance in modern Europeans were already present in this hunter-gatherer.
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Spanish hunter-gatherer had blue eyes and dark skin
La Braña 1, name used to baptize a 7,000 years old individual from the Mesolithic Period, whose remains were recovered at La Braña-Arintero site in Valdelugueros (León, Spain) had blue eyes and dark skin. These details are the result of a study conducted by Carles Lalueza-Fox, researcher from the Spanish National Research Council (CSIC), in collaboration with the Centre for GeoGenetics (Denmark). La Braña 1 represents the first recovered genome of an European hunter-gatherer. The research is published in Nature
The skeleton of La Braña 1, as it was discovered in 2006 [Credit: J.M. Vidal Encina]
The Mesolithic, a period that lasted from 10,000 to 5,000 years ago (between the Paleolithic and the Neolithic), ends with the advent of agriculture and livestock farming, coming from the Middle-East. The arrival of the Neolithic, with a carbohydrate-based diet and new pathogens transmitted by domesticated animals, entailed metabolic and immunological challenges that were reflected in genetic adaptations of post-Mesolithic populations. Among these is the ability to digest lactose, which La Braña individual could not do. Lalueza-Fox states: "However, the biggest surprise was to discover that this individual possessed African versions in the genes that determine the light pigmentation of the current Europeans, which indicates that he had dark skin, although we can not know the exact shade."
La Braña 1, the name used to baptize a 7,000-year-old individual from the Mesolithic Period, had blue eyes and dark skin [Credit: Spanish National Research Council]
CSIC researcher, who works at the Institute of Evolutionary Biology (a joint centre of CSIC and the University Pompeu Fabra (UPF), located in Barcelona, adds: "Even more surprising was to find that he possessed the genetic variations that produce blue eyes in current Europeans, resulting in a unique phenotype in a genome that is otherwise clearly northern European." The study of the genome suggests that current populations nearest to La Braña 1 are in northern Europe, such as Sweden and Finland. In addition, the work points out that La Braña 1 has a common ancestor with the settlers of the Upper Paleolithic site of Mal'ta, located in Lake Baikal (Siberia), whose genome was recovered a few months ago. Lalueza-Fox concludes: "These data indicate that there is genetic continuity in the populations of central and western Eurasia. In fact, these data are consistent with the archeological remains, as in other excavations in Europe and Russia, including the site of Mal'ta, anthropomorphic figures -called Paleolithic Venus- have been recovered and they are very similar to each other."
Frontal view of the La Braña 1 skull [Credit: J.M. Vidal Encina]
DNA with an "exceptional" preservation La Braña-Arintero site was discovered by chance in 2006 and excavated by Julio Manuel Vidal Encinas, archeologist of the Council of Castilla y León. The cave, located in a cold mountainous area with a steady temperature and 1,500 meters below the sea level, contributed to the "exceptional" preservation of the DNA from two individuals found inside, and they were called La Braña 1 and La Braña 2. According to Iñigo Olalde, lead author of the study, "the intention of the team is to try to recover the genome of the individual called La Braña 2, which is worse preserved, in order to keep obtaining information about the genetic characteristics of these early Europeans." Source: Spanish National Research Council (CSIC) [January 26, 2014]
Read more at: http://archaeologynewsnetwork.blogspot.it/2014/01/spanish-hunter-gatherer-had-blue-eyes.html?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed:+TheArchaeologyNewsNetwork+(The+Archaeology+News+Network)#.UubaP4vX__Q
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